Mechanism of the cell death induced by joint activation of p53 and ISR networks (Mechanismus buněčné smrti indukované současnou aktivací p53 a ISR)
- Brno, Czech
- Medical sciences
- Zdenek Andrysik
Doctoral study program: Biomedical Sciences Form: doctoral (present) Department: Department of Biology Supervisor: Zdenek Andrysik, Ph.D. Ph.D. position: Mechanism of the cell death induced by joint activation of p53 and ISR networks (Mechanismus buněčné smrti indukované současnou aktivací p53 a ISR) Annotation: TP53, which encodes transcription factor p53, is the most frequently mutated tumor suppressor gene in human cancers. Various types of cellular stress induce p53, which then transactivates a broad range of genes involved in numerous anti-cancer programs, including cell cycle arrest, DNA
Intratumoral heterogeneity in cellular response to p53 and ISR activation
- Brno, Czech
- Medical sciences
- Zdenek Andrysik
Doctoral study program: Biomedical Sciences Form: doctoral (present) Department: Department of Biology Supervisor: Zdenek Andrysik, Ph.D. Ph.D. position: Intratumoral heterogeneity in cellular response to p53 and ISR activation Annotation: The most frequently mutated tumor suppressor gene in human cancers is TP53, which encodes transcription factor p53. Induced by various types of cellular stress, p53 transactivates a broad range of genes involved in numerous anti-cancer programs including cell cycle arrest, DNA repair, senescence, and apoptosis. However, targeted induction of p53 by small mol
Identification and functional characterization of post translational-mediated controls acting during meiosis in C. elegans
- Brno, Czech
- Medical sciences
- Dr. Nicola Silva
Doctoral study program: Biomedical Sciences Doctoral study specialization: Biochemistry and Molecular Biology Form: doctoral present Department: Department of Biology, Faculty of Medicine MU Supervisor: Dr. Nicola Silva, Ph.D. Ph.D. position: Identification and functional characterization of post translational-mediated controls acting during meiosis in C. elegans Annotation: Meiosis is essential to generate functional gametes so to ensure perpetuation of species. Many processes take place during germ cells maturation in order to produce oocyte and sperm, including chromosome synapsis and DNA r
PhD Candidate: How do viruses hijack the cell's protein factory
- Brno, Czech
- Biological sciences Biological sciences
- Petra Linhartova
Come to CEITEC MU in Brno and join us! We are passionate structural biologists at CEITEC looking for PhD Candidate: How do viruses hijack the cell's protein factory We're excited to announce an open PhD student position in Gabriel Demo's Research Group! About this position: Are you fascinated by viruses, ribosomes, and cutting-edge structural biology techniques? Join our team at CEITEC Masaryk University and investigate how viruses coordinate genome replication with protein synthesis inside infected cells. Viruses rely entirely on host cells to produce their proteins. Recent advances in cryo-e
Wide-Bandgap Electronics for Energy Conversion
- Prague, Czech
- Physics
- Prof. Jan Vobecký
Pictus PhD Fellowship Programme Czech Technical University in Prague – International PhD Programme (PICTUS) will recruit 8 students (see Eligibility criteria below) for a full 48-month employment contract and enroll them in a specific PhD course. Candidates should prepare their own research proposal from the List of topics for the 2nd Call . Application form should be filled and all required documents uploaded using the dedicated electronic form. helpdesk: pictus@cvut.cz Guide for Applicants Wide-Bandgap Electronics for Energy Conversion Description: Semiconductor devices are at the heart of e
Superintegrability in classical and quantum mechanics
- Prague, Czech
- Physics
- Dr. Ian Marquette
Pictus PhD Fellowship Programme Czech Technical University in Prague – International PhD Programme (PICTUS) will recruit 8 students (see Eligibility criteria below) for a full 48-month employment contract and enroll them in a specific PhD course. Candidates should prepare their own research proposal from the List of topics for the 2nd Call . Application form should be filled and all required documents uploaded using the dedicated electronic form. helpdesk: pictus@cvut.cz Guide for Applicants Superintegrability in classical and quantum mechanics Description: Analytical investigation of dynamica
Study of novel scintillator materials for high-energy physics and applications
- Prague, Czech
- Technology
Pictus PhD Fellowship Programme Czech Technical University in Prague – International PhD Programme (PICTUS) will recruit 8 students (see Eligibility criteria below) for a full 48-month employment contract and enroll them in a specific PhD course. Candidates should prepare their own research proposal from the List of topics for the 2nd Call . Application form should be filled and all required documents uploaded using the dedicated electronic form. helpdesk: pictus@cvut.cz Guide for Applicants Study of novel scintillator materials for high-energy physics and applications Desription: Plastic scin
Quantum metrology of electrical quantities
- Prague, Czech
- Technology
- Ing. Jan Kučera
Pictus PhD Fellowship Programme Czech Technical University in Prague – International PhD Programme (PICTUS) will recruit 8 students (see Eligibility criteria below) for a full 48-month employment contract and enroll them in a specific PhD course. Candidates should prepare their own research proposal from the List of topics for the 2nd Call . Application form should be filled and all required documents uploaded using the dedicated electronic form. helpdesk: pictus@cvut.cz Guide for Applicants Quantum metrology of electrical quantities Description: Quantum metrology of electrical quantities is c
Novel methods of demolition waste recognition and classification
- Prague, Czech
- Technology
Pictus PhD Fellowship Programme Czech Technical University in Prague – International PhD Programme (PICTUS) will recruit 8 students (see Eligibility criteria below) for a full 48-month employment contract and enroll them in a specific PhD course. Candidates should prepare their own research proposal from the List of topics for the 2nd Call . Application form should be filled and all required documents uploaded using the dedicated electronic form. helpdesk: pictus@cvut.cz Guide for Applicants Description: Novel Methods of Demolition Waste Recognition and Classification is a project focused on t
Multiscale, Stochastic and Data-Driven Modeling of Materials and Processes
- Prague, Czech
- Computer science
Pictus PhD Fellowship Programme Czech Technical University in Prague – International PhD Programme (PICTUS) will recruit 8 students (see Eligibility criteria below) for a full 48-month employment contract and enroll them in a specific PhD course. Candidates should prepare their own research proposal from the List of topics for the 2nd Call . Application form should be filled and all required documents uploaded using the dedicated electronic form. helpdesk: pictus@cvut.cz Guide for Applicants Multiscale, Stochastic and Data-Driven Modeling of Materials and Processes Description: Predictive simu
Multilevel Modeling of Outcome Predictors Following Subthalamic Deep Brain Stimulation in Parkinson’s Disease
- Prague, Czech
- Computer science
- Dr. Karsten Mueller
Pictus PhD Fellowship Programme Czech Technical University in Prague – International PhD Programme (PICTUS) will recruit 8 students (see Eligibility criteria below) for a full 48-month employment contract and enroll them in a specific PhD course. Candidates should prepare their own research proposal from the List of topics for the 2nd Call . Application form should be filled and all required documents uploaded using the dedicated electronic form. helpdesk: pictus@cvut.cz Guide for Applicants Multilevel Modeling of Outcome Predictors Following Subthalamic Deep Brain Stimulation in Parkinson’s D
Magnetic sensors and actuators
- Prague, Czech
- Technology
- Dr. Renata Styblikova
Pictus PhD Fellowship Programme Czech Technical University in Prague – International PhD Programme (PICTUS) will recruit a total of 23 PhD students (see Eligibility criteria below) for a full 48-month employment contract and enroll them in a specific PhD course. Candidates should prepare their own research proposal from the topics offered . Application form should be filled and all required documents uploaded using the dedicated electronic form. helpdesk: petra.koudelova@fsv.cvut.cz Magnetic sensors and actuators Description: Example of project is the development of novel position sensor or ac
Liquid Phase Chemistry of Homologues of Superheavy Elements
- Prague, Czech
- Chemistry
Pictus PhD Fellowship Programme Czech Technical University in Prague – International PhD Programme (PICTUS) will recruit 8 students (see Eligibility criteria below) for a full 48-month employment contract and enroll them in a specific PhD course. Candidates should prepare their own research proposal from the List of topics for the 2nd Call . Application form should be filled and all required documents uploaded using the dedicated electronic form. helpdesk: pictus@cvut.cz Guide for Applicants Liquid Phase Chemistry of Homologues of Superheavy Elements Description: A new joint CTU – University o
Learning while searching in symbolic planners
- Prague, Czech
- Technology
Pictus PhD Fellowship Programme Czech Technical University in Prague – International PhD Programme (PICTUS) will recruit 8 students (see Eligibility criteria below) for a full 48-month employment contract and enroll them in a specific PhD course. Candidates should prepare their own research proposal from the List of topics for the 2nd Call . Application form should be filled and all required documents uploaded using the dedicated electronic form. helpdesk: pictus@cvut.cz Guide for Applicants Learning while searching in symbolic planners Description: The symbolic search in large state spaces is
Innovative processes and equipment in green materials, chemicals, and advanced biofuels production technologies
- Prague, Czech
- Technology
Pictus PhD Fellowship Programme Czech Technical University in Prague – International PhD Programme (PICTUS) will recruit 8 students (see Eligibility criteria below) for a full 48-month employment contract and enroll them in a specific PhD course. Candidates should prepare their own research proposal from the List of topics for the 2nd Call . Application form should be filled and all required documents uploaded using the dedicated electronic form. helpdesk: pictus@cvut.cz Guide for Applicants Innovative processes and equipment in green materials, chemicals, and advanced biofuels production tech
High-Velocity Dust Impacts on Tungsten Plasma-Facing Materials: A Predictive Multi-Scale Modeling Framework with Experimental Validation
- Prague, Czech
- Computer science
Pictus PhD Fellowship Programme Czech Technical University in Prague – International PhD Programme (PICTUS) will recruit 8 students (see Eligibility criteria below) for a full 48-month employment contract and enroll them in a specific PhD course. Candidates should prepare their own research proposal from the List of topics for the 2nd Call . Application form should be filled and all required documents uploaded using the dedicated electronic form. helpdesk: pictus@cvut.cz Guide for Applicants High-Velocity Dust Impacts on Tungsten Plasma-Facing Materials: A Predictive Multi-Scale Modeling Frame
Explainable end-to-end differentiable perception for self-supervised learning in robotics
- Prague, Czech
- Computer science
- Prof. Tomáš Svoboda
Pictus PhD Fellowship Programme Czech Technical University in Prague – International PhD Programme (PICTUS) will recruit 8 students (see Eligibility criteria below) for a full 48-month employment contract and enroll them in a specific PhD course. Candidates should prepare their own research proposal from the List of topics for the 2nd Call . Application form should be filled and all required documents uploaded using the dedicated electronic form. helpdesk: pictus@cvut.cz Guide for Applicants Explainable end-to-end differentiable perception for self-supervised learning in robotics Description:
Accelerator mass spectrometry in analysis of environmental samples
- Prague, Czech
- Chemistry
Pictus PhD Fellowship Programme Czech Technical University in Prague – International PhD Programme (PICTUS) will recruit 8 students (see Eligibility criteria below) for a full 48-month employment contract and enroll them in a specific PhD course. Candidates should prepare their own research proposal from the List of topics for the 2nd Call . Application form should be filled and all required documents uploaded using the dedicated electronic form. helpdesk: pictus@cvut.cz Guide for Applicants Accelerator mass spectrometry in analysis of environmental samples Description: A joint AMS laboratory
CFD Modelling of Multiphase Flows in Complex and Non-Newtonian Fluids
- Prague, Czech
- Engineering
Multiphase flows are important in many chemical, pharmaceutical, biotechnology, and food-processing applications. This PhD project will focus on computational modelling of gas–liquid (G–L), liquid–liquid (L–L), and solid–liquid (S–L) systems, with particular emphasis on processes involving non-Newtonian fluids. Building on our previous work on modelling bubbles, droplets, and particles in Newtonian systems, the project will extend existing CFD approaches to situations in which viscosity varies with shear rate and may also change over time. The candidate will develop and analyse CFD simulations
PhD Candidate in (Un) Structural Biology of Wnt Signaling
- Brno, Czech
- Biological sciences
Come to CEITEC MU in Brno and join us! We are Tripsianes group CEITEC MUNI , looking for a PhD Candidate in (Un) Structural Biology of Wnt Signaling About this position Dishevelled (DVL) is the central hub of Wnt signal transduction that integrates and transduces upstream signals through distinct cytoplasmic cascades. Looking at the many DVL faces reported in literature, three salient features underlying its function in signaling can be highlighted: (1) it interacts with more than seventy binding partners, (2) it is heavily phosphorylated at multiple sites by at least eight different kinases,