Investment Lead, Intercept

Intercept is looking for an experienced biotech/biohealth investor to join our team.

We’re working to make sure the portfolio of technologies needed to radically reduce the burden of respiratory viruses exists. We have two main focus areas: air-cleaning technologies (ACT’s) and broad-spectrum preventatives (BSPs). For BSPs, our goal is to advance 2+ products that meet our target product profile through Phase 2. We make both grants and investments, using the most capital-efficient tool to advance our target product profile.

Initially, this role will be focused on building internal investment processes, investment thesis, and supporting Intercept in establishing the investment function. Ultimately this role will focus on sourcing, diligencing, and executing on pipeline opportunities to make equity and/or grant investments in companies that have the most promising BSPs against our target product profile (TPP). In addition, the role will be responsible for portfolio management to make sure portfolio projects successfully advance their products by helping to remove bottlenecks and accelerate timelines. To effectively accomplish this work, the Investment Lead will develop views on the most promising approaches, identify new cutting edge areas of science, understand key product development inflection points, including mapping key technical and clinical/regulatory bottlenecks and developing plans to de-risk / mitigate them.

We need someone who can go deep on scientific and development diligence while also zooming out to synthesize how findings impact our capital deployment plan and long-term goals. A successful candidate will be action-oriented and comfortable working independently (vs. waiting to be told what to do) and a great communicator who can translate complex science for diverse audiences.

Intercept is a small team; you'll work with the entire team, many partners, and wear many hats. You'll own specific outcomes end-to-end and have a chance to contribute to BSP strategy over time.

• Expand the pipeline of candidates. Proactively engage networks (researchers, investors, founders, funders, etc.) to source new ideas and technologies. Manage referral channels (open RFP, referrals, etc.) and screen investment and grant opportunities.
• Own projects through diligence and transaction execution. Advance companies through early and deep / technical diligence: evaluating science quality, development plans, team, and fit against our TPP. Drive the investment or grantmaking process, coordinating with internal and external legal and diligence consultants. Bring projects through internal approval processes and act as the internal owner/champion.
• Develop points of view on technologies. Contribute to publishing a POV for the 5-10 most promising approaches (i.e., siRNA, T-cell vaccine, innate immune stimulators) and identify the key 'gating datapoints' that would make us kill or double down on that approach and when we'll get that datapoint (or if there is a gap).
• Build and maintain the CRM. Help ensure our CRM captures ~all known projects, and we have a process to systematically learn about/capture the best new projects early.
• Portfolio management. Supporting portfolio projects and leading on efforts to accelerate and support projects post investmentDetermine what would let the top projects in the field move 2x faster beyond funding and make sure those things happen.
• Map demand-side bottlenecks. Help map key stakeholders and address key evidence needs and bottlenecks across regulatory, clinical, recommendations, reimbursement and adoption/uptake.

Future opportunities for growth

• Lead investments independently. Grow into a more senior team lead, owning deals from start to finish, managing investment teams, and generating / pursuing new investment theses.
• Shape capital deployment. Contribute to our capital deployment plan informed by a clear POV of the most promising approaches.