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Post-Doctoral Fellowships in Physiology

FAPESP - São Paulo Research Foundation · Brazil

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About this position

Activities and context: The project aims to investigate opsin-mediated skin responses to different wavelengths of visible light and temperatures, focusing on proliferation, melanogenesis, oxidative stress, inflammation, the visual cycle, and lipofuscinogenesis, both in vivo and in vitro.

The fellows will be responsible for generating Opn2, Opn3, and Opn5 knockout cell lines using CRISPR/Cas9, as well as for analyzing gene and protein expression, signaling pathways, the skin microbiome, systemic cytokines, and comparative proteomics. The findings will also be validated using 3D skin models.

Mandatory requirements: Experience in molecular biology, omics and related fields.

Requirements Qualifications: Experience with laboratory animal handling, cell culture techniques, CRISPR-based approaches, gene and protein expression analyses, and microbiome analysis using shotgun sequencing.

How to apply: Send CV, letter of interest, two reference letters, and Ph. D. academic record.

This opportunity is open to candidates of any nationality. The selected candidate will receive a FAPESP Post-Doctoral fellowship in the amount of R$ 12,570.00 monthly and a research contingency fund, equivalent to 10% of the annual value of the fellowship which should be spent on items directly related to the research activity.

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