Postdoctoral researcher

About this position

Presentation of Sorbonne University :

To transmit knowledge, understand the world and meet the challenges of the 21st century, a new university was created on 1 January 2018, following the merger of Paris-Sorbonne University and Pierre and Marie Curie University.

Sorbonne University

is a multidisciplinary, research-intensive, world-class university. Based in the heart of Paris and present across the region, it is committed to student success and to addressing the scientific challenges of the 21st century.

www.sorbonne-universite.fr

The team led by Dr Fabienne Foufelle, entitled "Metabolic diseases, diabetes and comorbidities", is Team 5 of the UMRS 1166 research unit

(Inserm / Sorbonne University), integrated within the ICAN University Hospital Institute at Pitie-Salpetriere Hospital in Paris. The team's objective is to study the comorbidities of type 2 diabetes, such as insulin resistance and non-alcoholic fatty liver disease, and their relationship with lipid metabolism. There is strong continuity between basic and clinical research, thanks to the joint presence of researchers and clinicians (diabetology and hepatology departments at Pitie-Salpetriere Hospital).

Location:

UMRS 1166, 91 Bd de l’Hopital, 75013 PARIS, France.

Mission :

Define the optimized configuration of an “on-chip” device for adipocyte culture (*adipose tissue-on-chip*)

Main activities :

Develop advanced cell-culture methods in microdevices

Characterize the impact of the secretome on other cell types (hepatocytes, Kupffer cells, etc.)

Isolate mature adipocytes from rodents and humans

Isolate adipocyte precursors from rodents and humans and differentiate them into adipocytes in vitro

Supervision: NO

Knowledge and Skills

:

Required cross-disciplinary knowledge:

Cell models of adipose and hepatic tissues, metabolic pathophysiology

Technical skills:

Cell culture, cell signaling studies

Transferable skills:

Review of the literature relevant to the research topic

Interpersonal skills :

Scientific autonomy; Ability to work in a team and collaborate