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Postdoctoral Position – Cancer Immunology & Immunometabolism

iGRED · France

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About this position

Projet : Microenvironment Metabolism-Adapted Vaccination for Enhanced Reactivation of Immunosurveillance in Advanced Prostate Cancer.

The NuReP team (Nuclear Receptors & Pathophysiology) at iGReD – Université Clermont Auvergne/CNRS/Inserm is seeking a highly motivated postdoctoral researcher to join the INCa-funded MAVERIC project.

The successful candidate will play a central role in the project and will:

  • Develop and characterize genetically engineered and orthotopic prostate cancer models (CRISPR, lineage tracing,

surgery).

  • Investigate dendritic-cell and antitumor immune responses following LXR modulation and vaccination.
  • Perform spectral cytometry, cell sorting, scRNA-seq and spatial transcriptomics, including downstream data analysis.
  • Conduct cellular and molecular experiments using tumor and immune-cell models.
  • Collaborate with chemists developing novel LXR ligands and with the multidisciplinary MAVERIC consortium.
  • Contribute to publications, international conferences and dissemination of project findings.

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