About this position
The University of Stavanger invites applicants for a two year position as Researcher in Cancer Nanomedicine at the Faculty of Science and Technology, Department of Chemistry, Bioscience and Environmental Engineering.
The position is vacant from January 2027.
The hired researcher will mainly contribute to the research project and to innovation and value creation based on research results. The researcher must also contribute to the development of collaboration with industry and to the use of research-based knowledge in society.
The position is funded by The Research Council of Norway.
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About the research project
This research project, conducted at the University of Stavanger, investigates targeted lipid nanoparticles (LNPs) carrying therapeutic RNA as a potential treatment strategy for HER2-positive breast cancer. The study employs an in vivo zebrafish embryo model to evaluate the efficacy and biodistribution of these RNA-based nanocarriers. The research includes identifying and selecting therapeutic microRNAs, encapsulating them within ligand-functionalized lipid nanoparticles to target HER2+ cells, and validating their anti-cancer activity in zebrafish xenotransplants of both established breast cancer cell lines and patient-derived cell models.
The successful candidate will work with zebrafish models of breast cancer and will evaluate the effects of nanoparticles targeting HER2-positive cells, both when these cells form solid tumors and when they are circulating tumor cells.
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