Seeking a few Research Scientists or Postdoctoral Researchers (25-2982)(Biophenomena Engineering RIKEN ECL Research Team)

About this position

[Background of the recruitment and description of the project]

• Background of the recruitment and description of the project

The Biophenomena Engineering RIKEN ECL Research Team aims to establish novel therapeutics for hard-to-treat diseases by investigating the wealth of biological processes and modifying cells using molecular tools derived from unique biological systems. To achieve this goal, we are mining novel biological systems from databases using AI-driven tools, characterizing their functions through biochemical analysis, engineering them as molecular tools, and applying these novel tools in disease models. Recently, we are actively working on RNA-guided systems, such as the well-known CRISPR-Cas, which is widely used for genome editing technology, aiming to more precisely regulate biological processes involving DNA and RNA.

【Keywords】Cryo-EM,Evolution,NGS,Bioinformatics,Bioengineering

• details of the business

RIKEN is Japan's largest and most comprehensive research organization for basic and applied science.

[Work content and job description]

The successful candidate will investigate uncharacterized biological systems such as Fanzor and TIGR-Tas using molecular biology, and biochemical methods. The candidate is also expected to engineer the systems as molecular tools for therapeutic applications. In particular, the candidate is expected to actively pursue research using expertise in at least one of the areas listed in 1–3 below.

1.Structural analysis of biomacromolecular complexes using cryo-electron microscopy (cryo-EM)

2.Large-scale molecular phylogenetic analysis using sequence data

3.Functional analysis using next-generation sequencing (NGS) technologies, including RNA-seq, ChIP-seq, and a broad range of other sequencing-based methods

The job description may be changed during the contract period or upon contract renewal to the extent described above.

• Assigned department

Existing departments

[Work location]

• Address

351-0198 Saitama ,2-1 Hirosawa, Wako, RIKEN Wako Campus

RIKEN may order the employee to change work locations, if necessary.

[Number of hired]

Number of hired:1 person(s)

Number of hired description:Research Scientist or Postdoctoral Researcher: a few positions

In principle, Postdoctoral Researcher is defined as those with a doctoral degree of 5 years or less.

Research Scientist is defined as those with a doctoral degree more than 5 years.

The applicant will be assigned to an appropriate position based on his/her ability, aptitude, etc.

The difference in positions is as follows:

• Research Scientist: Carries out research and other work in accordance with laboratory research themes.

• Postdoctoral Researcher: Carries out research and other work in accordance with laboratory research themes under the mentorship and training of supervisors.

Job content supplemental explanation:Start of Employment

As early as possible