Postdoctoral Fellow

About this position

University of Colorado Anschutz

Department: Division of Hematology, Department of

Medicine

Job Title: Postdoctoral Fellow

Position #00853470 – Requisition #41226

Job Summary:

• This position reports directly to Dr. Austin Gillen and is
• responsible for developing, executing, and analyzing data from
• research projects investigating how post-transcriptional
• regulation, RNA processing, and cellular heterogeneity shape cancer
• cell states in myeloid malignancies (e.g., acute myeloid leukemia
• and myelodysplastic neoplasms). The position is an opportunity for
• a bright, creative, and enthusiastic individual to advance their
• career by performing impactful, cutting-edge biomedical research
• that integrates wet-lab experimentation with computational and
• bioinformatic analysis.

Key Responsibilities :

This position is expected to work independently under the guidance

of the principal investigator. Projects will involve extensive

development and use of single-cell genomic techniques,

high-throughput profiling, flow cytometry, molecular biology, and

computational analysis on patient-derived samples and cell line

models of hematologic malignancy. Specific duties include:

• Design and execute single-cell genomic experiments (e.g., single-cell RNA sequencing and related single-cell/multi-omic assays) on patient-derived and model samples.
• Contribute to high-throughput screening and profiling efforts, including analysis of large patient cohorts and/or functional assays, to identify mechanisms of disease progression and treatment resistance.
• Perform bioinformatic analysis of single-cell and genomic datasets, including scripting and pipeline development in R and/or Python.
• Contribute to the development, testing, and maintenance of reproducible software tools and computational methods for single-cell and genomic data analysis, in collaboration with the lab's methods-development efforts.
• Develop and apply flow cytometry, molecular biology, and cell biology assays to generate and validate experimental findings.
• Design and implement projects relating to the laboratory's overall research program.
• Analyze, interpret, and fully document experimental results.
• Collaborate with computational and clinical colleagues across the Division of Hematology and Department of Medicine on shared datasets and cross-disciplinary projects.
• Prepare data and manuscripts for publication.
• Prepare grant proposals to obtain independent post-doctoral funding.
• Actively participate in and present data at group meetings, journal clubs, and conferences.
• Work in conjunction with the PI and other lab staff to achieve programmatic goals, including student and staff mentorship.
• To fulfill job requirements, candidates must receive training and adhere to institutional standards of best practice in laboratory safety, biosafety, data security, and other areas as determined by the institution and/or PI.
• Other duties as assigned.

Work Location:

• Onsite - this role is expected to work onsite and is located on the
• University of Colorado Anschutz Medical Campus, Aurora,
• Colorado.

Why Join Us:

• The Gillen Lab is based in the Division of Hematology, Department
• of Medicine, at the University of Colorado Anschutz Medical Campus,
• led by Principal Investigator Dr. Austin Gillen. The lab runs an
• integrated bench-and-computational research program studying how
• RNA processing and cellular heterogeneity shape cancer cell states,
• with a particular focus on myeloid malignancies. Fellows are
• trained across the full research pipeline - experimental design,
• data generation, computational analysis, visualization, and
• manuscript/grant preparation - within a collaborative,
• interdisciplinary environment spanning hematology, oncology, and
• computational biology across CU Anschutz.

Why work for the University?

• The University of Colorado offers a comprehensive benefits package.
• To see what benefits are available for Post-Doctoral Fellows,
• please visit:

Payroll & Benefits Orientation for Post-Doctoral Fellows |

University of Colorado (cu.edu)

Comprehensive Benefits Guide for Post-Doctoral Fellows

(cu.edu)

Qualifications:

Minimum Qualifications:

Applicants must meet minimum qualifications at the time of

hire.

• A doctoral level degree (PhD, MD, MD/PhD) in molecular biology, genomics, immunology, or equivalent from an accredited institution.
• At least one first-author publication in an internationally recognized, peer-reviewed journal.

Conditions of Employment:

• Candidates must be able to work with human biospecimens and other potentially biohazardous research materials.

Preferred Qualifications:

• Graduate training in a biomedical laboratory setting studying molecular biology, genomics, immunology, hematology, or a related field.
• Experience with single-cell genomic techniques (e.g., single-cell RNA sequencing, single-cell multi-omic or spatial profiling).
• Experience with high-throughput screening approaches or analysis of large-scale genomic or clinical datasets.
• Proficiency in R and/or Python for bioinformatic analysis, including common single-cell analysis toolkits, and experience working in high-performance computing (HPC) environments.
• Experience with flow cytometry and standard molecular and cell biology techniques (e.g., cell culture, nucleic acid extraction, cloning).
• Experience processing, harmonizing, and quality-controlling single-cell datasets at production scale (e.g., building or maintaining an analysis pipeline across a multi-sample clinical cohort spanning hundreds of specimens) rather than single-experiment analyses alone.

Knowledge, Skills and Abilities:

• Excellent written and verbal communication skills.
• Ability to work independently and as a team member within a research environment.
• Ability to work efficiently and effectively with computer software, including common bioinformatic/statistical software and Microsoft Office.
• Skilled with the use of aseptic mammalian cell culture techniques.
• Skilled with common laboratory techniques and equipment, and/or computational and statistical analysis methods, consistent with PhD-level graduate training.
• Ability to commit to an independent scientific career in cancer biology, genomics, or a related field, with a proven high degree of independence and self-motivation to achieve these ends.
• Ability to work a flexible schedule based on the needs of the project.

How to Apply:

For full consideration, please submit the following

document(s):

• A letter of interest describing relevant job experiences as they relate to listed job qualifications and interest in the position

• Curriculum vitae / Resume

• Five professional references including name, address, phone number (mobile number if appropriate), and email address

Applications are accepted electronically ONLY at www.cu.edu/cu-careers .

Questions should be directed to: Daniel Page –

daniel.page@cuanschutz.edu

Screening of Applications Begins:

Immediately and continues until October 15, 2026.

Anticipated Pay Range:

The starting salary range (or hiring range) for this position has

been established as HIRING RANGE:

• Postdoctoral Fellow: $70,000 - $80,000

• The above salary range (or hiring range) represents the
• University's good faith and reasonable estimate of the range of
• possible compensation at the time of posting. This position is not
• eligible for overtime compensation unless it is non-exempt.

• Your total compensation goes beyond the number on your paycheck.
• The University of Colorado provides generous leave, health plans,
• and retirement contributions that add to your bottom line.

Total Compensation Calculator: http://www.cu.edu/node/153125

Equal Employment Opportunity Statement:

• The University of Colorado (CU) is an Equal Opportunity Employer
• and complies with all applicable federal, state, and local laws
• governing nondiscrimination in employment. We are committed to
• creating a workplace where all individuals are treated with respect
• and dignity, and we encourage individuals from all backgrounds to
• apply, including protected veterans and individuals with
• disabilities.

ADA Statement:

• The University will provide reasonable accommodations to applicants
• with disabilities throughout the employment application process. To
• request an accommodation pursuant to the Americans with
• Disabilities Act, please contact the Human Resources ADA
• Coordinator at hr.adacoordinator@ucdenver.edu
• ​.

Background Check Statement:

• The University of Colorado Anschutz Medical Campus is dedicated to
• ensuring a safe and secure environment for our faculty, staff,
• students and visitors. To assist in achieving that goal, we conduct
• background investigations for all prospective employees.

Vaccination Statement:

• CU Anschutz strongly encourages vaccination against the COVID-19
• virus and other
• vaccine preventable diseases . If you work, visit, or volunteer
• in healthcare facilities or clinics operated by our affiliated
• hospital or clinical partners or by CU Anschutz, you will be
• required to comply with the vaccination and medical surveillance
• policies of the facilities or clinics where you work, visit, or
• volunteer, respectively. In addition, if you work in certain
• research areas or perform certain safety sensitive job duties, you
• must enroll in the
• occupational health medical surveillance program .