About this position
We are seeking a highly ambitious and enthusiastic PhD candidate to join the Artegiani & Hendriks group. You will focus on understanding mechanisms of human liver function and disease through in vitro model development and mechanistic studies.
About our group and project
The Artegiani & Hendriks lab has strong interest in building relevant human in vitro models to understand disease development and progression, focusin on two main organs: the brain and the liver. Part of our research focuses on metabolic dysfunction-associated steatotic liver disease (MASLD), which impairs liver function and predisposes to liver cancer. In this project, you will use human organoids, CRISPR-Cas tools, -omic read-outs such as scRNA-sequencing, and advanced imaging tools to explore the role of metabolism in liver function and disease.
This 4-year PhD project is funded by a Vidi grant from the Dutch Research Council (NWO).
Your profile
We are looking for a highly motivated and committed scientist who is excited to address fundamental questions in liver biology.
You should have recently completed your MSc education, and have a background in molecular, cellular biology and/or stem cell and developmental biology, and has internship experience in competitive institutions.
Experience with bioinformatic tools or advanced imaging are a pro.
We are looking for a talented and highly motivated academic-oriented candidate that can work independently while thriving in a multidisciplinary and international research environment.
The group and the institute are international, and the work language is English.
The Princess Máxima Center
The Princess Máxima Center for Pediatric Oncology is a research hospital concentrating healthcare, research, and education of pediatric cancer in a single location in Utrecht. The institute aims to provide the highest level of care for all children with cancer and has the ambition to cure all children of cancer and improve quality of life. The center brings together the best possible care and scientific research, creating a unique interdisciplinary institute for pediatric oncology in Europe.
More information
When applying, please ensure that you include the following: 1) an up-to-date resume, 2) a short motivation letter (two-page maximum), 3) contact information of 2-3 references. Incomplete applications will not be considered. The vacancy will be open until a suitable candidate is found, and reviewing of potential candidates will start as soon as possible.
For more information about the Artegiani & Hendriks lab and research, visit: www.bendellab.com . For questions, you are welcome to contact Benedetta Artegiani and Delilah Hendriks both in a joint email at b.a.artegiani@prinsesmaximacentrum.nl and d.f.g.hendriks-7@prinsesmaximacentrum.nl
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