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Postdoctoral Position: Addressing the mechanical evolution of colorectal cancer

Gustave Roussy · INSERM U1279 · France

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About this position

The “Tumor Dynamics and Plasticity” group is a newly established research team at Institut Gustave Roussy (Villejuif, Paris) , led by Carlos Pérez-González. Our goal is to understand how mechanochemical signals regulate tumor cell state patterning and how these processes drive tumor progression and clinical outcome.

With the help of our recent ERC Starting Grant, we are building a multidisciplinary team at the interface of biology and physics, integrating mechanobiology, quantitative imaging and transcriptomics in organoids and tumors. Located within the largest cancer hospital in Europe, our lab benefits from access to patient-derived organoids, clinical samples, and oncology expertise.

We are seeking a highly motivated postdoctoral researcher with expertise in quantitative biology or bioinformatics. The candidate will develop multidisciplinary research bridging tissue mechanics and transcriptomics, with the goal of understanding how mechanical signals guide cancer cell plasticity. The project will involve developing pipelines to combine organoid force measurements with spatial omics approaches.

Ideally, the candidate should be interested in both wet- and dry-lab research, but wet-lab experience is not required.

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